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Arterial Stiffness and risk of disease – top 5 things you can do to keep your arteries flexible

Arterial stiffness isn’t quite the same as hardened arteries, but it can have the same devastating effects on your health. Fortunately, taking a few simple actions can prevent and even reverse arterial stiffness.

What is arterial stiffness?

Arterial stiffness is a gradual increase in the rigidity of your arteries. It’s closely related to atherosclerosis – the buildup of plaque in your arteries that leads to arterial hardening and vascular disease – and is a risk factor for developing atherosclerosis, but it’s not the same condition.

Your arteries have the ability to widen (dilate) or get narrower (constrict), depending on the needs of the tissues they’re supplying. It’s been known for years that the innermost layer of the artery (endothelium) is vulnerable to damage from common issues such as inflammation and high blood glucose, but research indicates that the middle layer of the artery (tunica media) also plays a vital role in blood flow regulation.

Arterial stiffness involves a loss of arterial suppleness, which affects dilation and constriction and prevents the arteries from regulating your blood flow and maintaining healthy blood pressure. The stiffness can extend into your capillaries, preventing these tiny blood vessels from delivering oxygen and nutrients to your organs.

Man pressing on chest with painful expression

What causes arterial stiffness?

One of the primary causes of arterial stiffness is aging. As you grow older, the tissues all around your body gradually stiffen and weaken as levels of elastin and collagen decline, and your arteries are no exception.

Type 2 diabetes, which results from high blood glucose levels, is also known to increase your risk of arterial stiffness and hypertension (high blood pressure). A third significant risk factor is calcification, where your blood leaves calcium deposits in the artery walls, making them harder. Smoking and cardiovascular disease are also risk factors for developing arterial stiffness.

What are the outcomes of having arterial stiffness?

Having arterial stiffness can contribute to a number of serious health problems, including:

  • Cardiovascular disease
  • Stroke
  • Alzheimer’s disease and other forms of dementia
  • Kidney failure
  • Parkinson’s disease
  • Non-alcoholic fatty liver disease
  • Type 2 diabetes

One of the major issues resulting from arterial stiffness is rising blood pressure. Hypertension (high blood pressure) also damages the walls of your arteries and makes them even stiffer.

How is arterial stiffness measured?

There are various ways of measuring arterial stiffness, but one of the most accurate is assessing central aortic pulse wave velocity. This involves recording pulse waves at both the carotid arteries in your neck and femoral arteries in your thighs and comparing them. Some devices use special blood pressure cuffs, while others use sensors.

When your heart contracts, a pulse of energy passes through your circulatory system. Arterial stiffness affects the speed at which this pulse wave travels, so measuring the aortic pulse wave is a good indicator of the stiffness of your arteries. With some methods, there’s a break required between measurements, but newer devices can do the two measurements synchronously.

What can I do to avoid arterial stiffness?

Here are the top five ways of avoiding arterial stiffness and keeping your arteries flexible:


Exercise is important for keeping all your tissues and organs healthy. It increases blood flow, which means your tissues get more oxygen and nutrients. It also prevents atrophy, where tissues weaken and lose function from lack of use.

Fish oil supplements

Fish oil supplements contain omega-3 fatty acids DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid). These substances reduce inflammation, clotting, and blood vessel constriction, which improves the flexibility of your arteries.

Vitamins D and K

Clinical trials of vitamin D3 and vitamin K2 show a significant reduction in the participants’ arterial stiffness, and one study suggests that arterial stiffness could be reversible using

high doses of vitamin D. Both vitamins D and K slow artery calcification and help maintain blood vessel suppleness.


Garlic increases nitric oxide activity in your body, which is important for healthy circulation and blood pressure. However, its chief benefit in keeping your arteries supple is the hydrogen sulfide it contains, a compound that relaxes your blood vessels and reduces blood pressure.

High nitrate diet

Nitrates in your food are a source of nitric oxide. Eating a diet containing vegetables rich in nitrates reduces your risk of developing hypertension and can improve cell function in the artery’s endothelial layer. You might be familiar with nitrates from their link with processed meats, but don’t confuse the two – processing alters nitrates in meat to produce a potentially cancer-causing chemical; this doesn’t happen with unprocessed sources of nitrates.

Considering the impact of arterial stiffness on your vascular health, it makes sense to adopt these straightforward dietary and lifestyle changes. The added bonus is that they all offer many more benefits to your health than just reducing your risk of arterial stiffness.

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