{"id":4325,"date":"2023-02-09T10:23:11","date_gmt":"2023-02-09T02:23:11","guid":{"rendered":"https:\/\/peakmetabolism.com\/?p=4325"},"modified":"2023-02-09T13:26:01","modified_gmt":"2023-02-09T05:26:01","slug":"%e3%80%90nmn%e5%b8%b8%e8%a6%8b%e5%95%8f%e9%a1%8c%e3%80%91%e4%ba%86%e8%a7%a3%e4%bb%80%e9%ba%bc%e6%98%afnmn%ef%bc%8c%e5%8e%9f%e7%90%86%e3%80%81%e5%8a%9f%e6%95%88%e5%92%8c%e5%89%af%e4%bd%9c%e7%94%a8","status":"publish","type":"post","link":"https:\/\/peakmetabolism.com\/zh-hant\/%e4%bb%a3%e8%ac%9d%e5%81%a5%e5%ba%b7\/%e3%80%90nmn%e5%b8%b8%e8%a6%8b%e5%95%8f%e9%a1%8c%e3%80%91%e4%ba%86%e8%a7%a3%e4%bb%80%e9%ba%bc%e6%98%afnmn%ef%bc%8c%e5%8e%9f%e7%90%86%e3%80%81%e5%8a%9f%e6%95%88%e5%92%8c%e5%89%af%e4%bd%9c%e7%94%a8\/","title":{"rendered":"\u3010NMN\u5e38\u898b\u554f\u984c\u3011\u4e86\u89e3\u4ec0\u9ebc\u662fNMN\uff0c\u539f\u7406\u3001\u529f\u6548\u548c\u526f\u4f5c\u7528\uff01"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"538\" src=\"https:\/\/peakmetabolism.com\/wp-content\/uploads\/2023\/02\/NMN-1024x538.jpg\" alt=\"\" class=\"wp-image-4326\" srcset=\"https:\/\/peakmetabolism.com\/wp-content\/uploads\/2023\/02\/NMN-1024x538.jpg 1024w, https:\/\/peakmetabolism.com\/wp-content\/uploads\/2023\/02\/NMN-300x158.jpg 300w, https:\/\/peakmetabolism.com\/wp-content\/uploads\/2023\/02\/NMN-768x403.jpg 768w, https:\/\/peakmetabolism.com\/wp-content\/uploads\/2023\/02\/NMN.jpg 1200w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2090123221001491\">\u03b2-Nicotinamide Mononucleotide\uff08\u03b2-\u7159\u9170\u80fa\u55ae\u6838\u82f7\u9178)<\/a>\uff0c\u7c21\u7a31NMN\uff0c\u662fNAD+ \uff08\u7159\u9170\u80fa\u817a\u560c\u5464\u4e8c\u6838\u82f7\u9178\uff09\u7684\u76f4\u63a5\u524d\u9ad4\u3002NMN\u53ef\u8f49\u5316\u6210\u4eba\u9ad4\u5fc5\u9808\u7684NAD+\uff0c\u4e00\u7a2e\u8eab\u9ad4\u5fc5\u9700\u7684\u8f14\u9176\uff0c\u4e5f\u662f\u4eba\u9ad4\u5167\u9664\u6c34\u4efd\u4ee5\u5916\u542b\u91cf\u6700\u591a\u7684\u5206\u5b50\u3002<\/p>\n\n\n\n<p>\u8eab\u9ad4\u6703\u5f9e\u524d\u9ad4\u4e2d\u7522\u751fNAD +\u3002\u9ad4\u5167\u5b58\u6709\u7684\u524d\u9ad4\u5305\u62ec<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7226615\/\">\u7159\u9170\u80fa<\/a>\uff08Nicotinamide\uff09\uff0c<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S155041312030190X\">\u7159\u9178<\/a>\uff08Niacin\uff09\uff0c<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S155041312030190X\">\u7159<\/a><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7226615\/\">\u9170\u80fa\u6838\u7cd6<\/a>\uff08Nicotinamide riboside\uff09\u548c<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S155041312030190X\">\u7159<\/a><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7238909\/\">\u91af\u80fa\u55ae\u6838\u82f7\u9178<\/a>\uff08NMN)\u3002\u9019\u4e9b\u524d\u9ad4\u5982\u7159\u9170\u80fa \uff0c\u7159\u9178\u548c\u7159\u9170\u80fa\u6838\u7cd6\u662f\u4e00\u7a2e\u7dad\u751f\u7d20B3\uff0c\u53ef\u4f86\u81ea\u98f2\u98df\u3002\u9032\u5165\u4eba\u9ad4\u5f8c\uff0c\u7d30\u80de\u6703\u901a\u904e\u4e0d\u540c\u7684\u9014\u5f91\u5408\u6210NAD+\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>NAD+ <\/strong><strong>\u7684\u76ca\u8655<\/strong><\/h2>\n\n\n\n<p>NAD+\u6703\u96a8\u5e74\u7d00\u589e\u9577\u800c\u6d41\u5931\uff0c\u4ee4\u8eab\u9ad4\u51fa\u73fe\u8870\u8001\u75c7\u72c0\u3002\u5b83\u7684\u91cd\u8981\u6027\u5305\u62ec:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31463647\/\">\u9810\u9632\u5fc3\u81df\u75c5\u548c\u8870\u8001\u76f8\u95dc\u7684\u8840\u7ba1\u529f\u80fd\u8870\u9000<\/a>\uff0c\u4f8b\u5982\u8840\u7ba1\u786c\u5316\u3001\u6c27\u5316\u6027\u640d\u50b7 \u3001\u7d30\u80de\u5206\u88c2\u80fd\u529b\u53d7\u640d\uff0c\u4fc3\u9032\u8840\u7ba1\u5065\u5eb7\uff0c\u751a\u81f3\u6703\u5f71\u97ff\u57fa\u56e0\u6d3b\u8e8d\u7a0b\u5ea6<\/li>\n\n\n\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5668137\/\">\u63d0\u9ad8\u808c\u8089\u8010\u529b\u548c\u529b\u91cf<\/a><\/li>\n\n\n\n<li>\u964d\u4f4e<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6511662\/\">\u4ee3\u8b1d\u75c7\u5019\u7fa4<\/a>\u98a8\u96aa\uff0c\u5982\u80a5\u80d6\u3001\u7cd6\u5c3f\u75c5\u3001\u8840\u8102\u7570\u5e38\u548c\u8102\u80aa\u809d<\/li>\n\n\n\n<li>NAD+\u80fd\u6fc0\u6d3b\u4e00\u7d44\u7a31\u70ba<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4112140\/#:~:text=Highlights-,NAD%2Bplays%20a%20key%20role%20in%20regulating%20metabolism%20and%20circadian,biosynthesis%20defect%20and%20increased%20depletion.\">sirtuins<\/a>\u7684\u9577\u58fd\u86cb\u767d\uff0c\u5f9e\u800c\u589e\u5f37 DNA \u4fee\u5fa9\u529f\u80fd<\/li>\n\n\n\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7973386\/\">\u589e\u5f37\u7dda\u7c92\u9ad4\u7684\u529f\u80fd<\/a>\uff0c\u80fd\u4fc3\u9032\u65b0\u9673\u4ee3\u8b1d\uff0c\u4ea6\u80fd\u9006\u8f49\u90e8\u5206\u7dda\u7c92\u9ad4\u529f\u80fd\u969c\u7919\u548c\u795e\u7d93\u7cfb\u7d71\u75be\u75c5\u5982\u963f\u8332\u6d77\u9ed8\u75c7<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u589e\u52a0NAD+\u6c34\u5e73<\/strong><\/h3>\n\n\n\n<p>\u9ad4\u5167\u7522\u751fNMN\u7684\u9176\u7a31\u70ba<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7238909\/\">NAMPT<\/a>\u3002 NAMPT\u662fNAD +\u751f\u7522\u4e2d\u7684\u9650\u901f\u9176\u3002 \u8f03\u4f4e\u6c34\u5e73\u7684NAMPT\u6703\u5c0e\u81f4NMN\u7522\u91cf\u4e0b\u964d\uff0c\u5f15\u81f4NAD +\u6c34\u5e73\u4e0b\u964d\u3002\u9069\u91cf\u7684\u904b\u52d5\u53ef\u4ee5\u6709\u6548\u63d0\u9ad8NAMPT\u6c34\u5e73 \u3002<\/p>\n\n\n\n<p>\u6dfb\u52a0\u985e\u4f3cNMN\u7684\u524d\u9ad4\u53ef\u4ee5\u52a0\u5febNAD +\u7684\u751f\u7522\uff0c\u800c\u9019\u53ef\u4ee5\u901a\u904e\u88dc\u5145NAD +\u7684\u524d\u9ad4\u5982NMN\u548c\u70df\u9170\u80fa\u6838\u7cd6\u3002 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0092867418301521\">\u4e00\u9805\u7814\u7a76<\/a>\u6307\u51fa\u88dc\u5145NAD+\u5fc5\u9808\u5229\u7528\u4ed6\u7684\u524d\u9ad4\u5206\u5b50\uff0c\u56e0\u70baNAD+\u4e0d\u80fd\u7a7f\u904e\u7d30\u80de\u819c\u9032\u5165\u7d30\u80de\u7121\u6cd5\u76f4\u63a5\u5438\u6536\u3002\u53e6\u5916\uff0c<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7752291\/\">\u7a7a\u8179\u6216\u6e1b\u5c11\u5361\u8def\u91cc\u7684\u651d\u5165<\/a>\u4e5f\u53ef\u4ee5\u589e\u52a0NAD 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href=\"https:\/\/www.nature.com\/articles\/s41598-022-18272-y\">\u4eba\u9ad4<\/a>\u7684\u7814\u7a76\u4e2d\u5df2\u8b49\u5be6\u670d\u7528NMN\u662f\u5b89\u5168\u7684\uff0c\u5373\u4f7f\u9577\u671f\u9577\u671f\u651d\u53d6\u9ad8\u6fc3\u5ea6\u7684NMM\uff0c\u4e5f\u6c92\u6709\u767c\u73fe\u4efb\u4f55\u6bd2\u6027\u53cd\u61c9\u6216\u526f\u4f5c\u7528\u3002<\/p>\n\n\n\n<p>\u96a8\u7740\u5e74\u7d00\u589e\u9577\uff0cNAD+\u6c34\u5e73\u6703\u4e0b\u964d\uff0c\u5f9e\u98df\u7269\u4e2d\u88dc\u5145NAD+\u7684\u524d\u9ad4\u7dad\u751f\u7d20B3\uff0c\u4fdd\u6301\u5145\u8db3\u7684\u904b\u52d5\uff0c \u6e1b\u5c11\u5361\u8def\u91cc\u7684\u651d\u5165\uff0c\u751a\u81f3\u9032\u98dfNMN\u7684\u71df\u990a\u88dc\u5145\u54c1\u6216\u6709\u52a9\u6e1b\u4f4e\u8870\u8001\u75c7\u72c0\u53ca\u9810\u9632\u5fc3\u8840\u7ba1\u75be\u75c5\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/wa.me\/85268906041\"><img decoding=\"async\" width=\"1024\" height=\"311\" src=\"https:\/\/peakmetabolism.com\/wp-content\/uploads\/2023\/02\/Peak-metabolism-cta-TC-114150-2-1024x311.jpg\" alt=\"\" class=\"wp-image-4370\" srcset=\"https:\/\/peakmetabolism.com\/wp-content\/uploads\/2023\/02\/Peak-metabolism-cta-TC-114150-2-1024x311.jpg 1024w, https:\/\/peakmetabolism.com\/wp-content\/uploads\/2023\/02\/Peak-metabolism-cta-TC-114150-2-300x91.jpg 300w, https:\/\/peakmetabolism.com\/wp-content\/uploads\/2023\/02\/Peak-metabolism-cta-TC-114150-2-768x233.jpg 768w, https:\/\/peakmetabolism.com\/wp-content\/uploads\/2023\/02\/Peak-metabolism-cta-TC-114150-2.jpg 1200w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>\u03b2-Nicotinamide 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